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Senior Scientist

Astrix • South San Francisco, CA 94083 • Posted 1 day ago via LinkedIn

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In-person • Full-time • $50.00-$65.00/hr • Senior Level

Job Highlights

Using AI ⚡ to summarize the original job post

Astrix is seeking a Senior Scientist specializing in Bio-conjugation to join their team. The role involves developing and optimizing bio-conjugation processes, purifying and characterizing antibody-drug conjugates, and applying advanced analytical techniques to support drug development. This position offers hands-on learning and professional growth in a fast-paced laboratory environment.

Responsibilities

  • Perform bio-conjugations of antibodies with linker-payload combinations using established protocols.
  • Utilize and optimize purification methods for biologics, such as size-exclusion chromatography (SEC), hydrophobic interaction chromatography (HIC), and ion-exchange chromatography.
  • Gather, analyze, and interpret data from analytical techniques, including liquid chromatography-mass spectrometry (LC/MS).
  • Collaborate with multidisciplinary teams to contribute to the discovery and development of novel therapeutics.
  • Enhance skills in reaction setup, route design, and optimization through on-the-job training.

Qualifications

Required

  • Bachelor’s, Master’s, or PhD in Chemistry, Biochemistry, or a related field.
  • Proven experience in bio-conjugation, purification, and characterization of antibody-drug conjugates.
  • Proficiency in analytical techniques such as HIC, reverse phase (RP), SEC, SDS-PAGE, and UV-Vis spectroscopy.
  • Strong foundation in protein biochemistry and chemistry.

Preferred

  • Experience with biologics analytics and advanced purification techniques.
  • Effective communicator with a collaborative mindset and a strong team-oriented approach.
  • Ability to manage timelines and work in a dynamic, results-driven environment.

Full Job Description

Our client is seeking a driven and collaborative Bio-conjugation Scientist to join their team. The role involves developing and optimizing bio-conjugation processes, purifying and characterizing antibody-drug conjugates, and applying advanced analytical techniques to support drug development. This position provides opportunities for hands-on learning and professional growth in a fast-paced laboratory environment.


Pay: $50-$65/hr


Key Responsibilities:

  • Perform bio-conjugations of antibodies with linker-payload combinations using established protocols.
  • Utilize and optimize purification methods for biologics, such as size-exclusion chromatography (SEC), hydrophobic interaction chromatography (HIC), and ion-exchange chromatography.
  • Gather, analyze, and interpret data from analytical techniques, including liquid chromatography-mass spectrometry (LC/MS).
  • Collaborate with multidisciplinary teams to contribute to the discovery and development of novel therapeutics.
  • Enhance skills in reaction setup, route design, and optimization through on-the-job training.


Qualifications:

  • Education: Bachelor’s, Master’s, or PhD in Chemistry, Biochemistry, or a related field.
  • Experience:
  • Proven experience in bio-conjugation, purification, and characterization of antibody-drug conjugates.
  • Proficiency in analytical techniques such as HIC, reverse phase (RP), SEC, SDS-PAGE, and UV-Vis spectroscopy.
  • Strong foundation in protein biochemistry and chemistry.
  • Bonus: Experience with biologics analytics and advanced purification techniques.

Skills:

  • Effective communicator with a collaborative mindset and a strong team-oriented approach.
  • Ability to manage timelines and work in a dynamic, results-driven environment.