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Associate Research Scientist

TSR Consulting Services, Inc. • Seattle, WA 98127 • Posted 2 days ago via LinkedIn

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In-person • Full-time • $63.00-$65.00/hr • Contract • Mid Level

Job Highlights

Using AI ⚡ to summarize the original job post

TSR Consulting Services, Inc. is seeking a local Associate Research Scientist for a contracting position with a leading pharmaceutical company in Seattle, WA. The role involves working on initiatives to drive next-generation LNP platform development focused on gene editing capabilities, including process development to produce and purify LNPs, characterization of LNPs, and exposure to a wide range of gene editing technologies. The position offers a unique opportunity to work collaboratively across different groups and contribute to lab maintenance and continuous improvement initiatives.

Responsibilities

  • Work on initiatives to drive next-generation LNP platform development focused on gene editing capabilities.
  • Become proficient in developing processes to produce and purify LNPs.
  • Gain familiarity with analytical assays for characterization of LNPs.
  • Execute and troubleshoot process development experiments supporting LNP production and purification.
  • Assist in the design of experiments and interpretation of data relating to LNP production and purification.
  • Manage the flow of samples and data and perform analyses.
  • Optimize workflows for assessing new modes of production and purification.
  • Support research-to-development transition endeavors, including early-stage/pipeline molecular assessment activities.
  • Actively participate and support lab maintenance and continuous improvement initiatives.
  • Maintain accurate and detailed laboratory notebook and documentation.
  • Summarize and present data in group meetings and contribute to group discussions and team strategy.
  • Author technical reports and study memos.

Qualifications

Required

  • Experience with production and purification of LNPs or molecule of similar nature
  • Degree in biological or chemical engineering, biochemistry, or bio-related field
  • Experience with handling of nucleic acids
  • Experience with LNP characterization techniques (HPLC, DLS, MALs, NTA, etc.)
  • Experience with downstream purification of biological molecules (AKTA, chromatography, TFF, viral filtration, etc.)
  • Experience with development of continuous processes and implementation process-analytical technologies (PATs)
  • Experience with microfluidic technologies
  • Experience in the development of other gene delivery or editing materials (e.g. adeno-, retro-, lenti-, RNPs, Cas, mRNA, etc.)
  • Demonstrated and extensive experience with TFF and sterile filtration of biological molecules
  • Experience with JMP for DoE design and analyses
  • Ability to leverage literature, internal and external resources to solve problems

Full Job Description

80267


TSR is a premier National U.S. Staffing company with over 50 years of staffing excellence.


Our client, a leading pharmaceutical company is hiring an Associate Research Scientist for a contracting position. Please ONLY local candidates to Seattle WA.


MUST Have :

  • Experience with production and purification of LNPs or molecule of similar nature
  • Degree in biological or chemical engineering, biochemistry, or bio-related field
  • Experience with handling of nucleic acids
  • Experience with LNP characterization techniques (HPLC, DLS, MALs, NTA, etc.)
  • Experience with downstream purification of biological molecules (AKTA, chromatography, TFF, viral filtration, etc.)
  • Experience with development of continuous processes and implementation process-analytical technologies (PATs)
  • Experience with microfluidic technologies
  • Experience in the development of other gene delivery or editing materials (e.g. adeno-, retro-, lenti-, RNPs, Cas, mRNA, etc.)



Work Location: Seattle WA


Pay: $63-65/hour W2


Required Skills:

  • Will be working on initiatives intended to drive next-generation LNP platform development focused on gene editing capabilities
  • Specifically, in the pursuit of end-to-end assessment of novel technologies and approaches, the associate will seek to become highly proficient in developing processes to produce and purify LNPs, while also gaining familiarity with analytical assays for characterization of LNPs
  • The associate will also have the unique opportunity to be exposed to a wide range of other gene editing technologies and will be encouraged to work collaboratively with a range of different groups doing different types of process development
  • Execute and troubleshoot process development experiments supporting LNP production and purification
  • Assist in the design of experiments and interpretation of data relating to LNP production and purification
  • Manage the flow of samples and data and perform analyses
  • Optimize workflows for assessing new modes of production and purification
  • Support research-to-development transition endeavors, including early-stage/pipeline molecular assessment activities
  • Actively participate and support lab maintenance and continuous improvement initiatives
  • Maintain accurate and detailed laboratory notebook and documentation
  • Summarize and present data in group meetings and contribute to group discussions and team strategy
  • Author technical reports and study memos
  • Demonstrated and extensive experience with TFF and sterile filtration of biological molecules
  • Experience with JMP for DoE design and analyses
  • Ability to leverage literature, internal and external resources to solve problems